Monday, July 19, 2010

Artificial Lung "Breathes" in Rats: Study

Reuters
July 16, 2010

From NursingLink

U.S. researchers have created a primitive artificial lung that rats used to breathe for several hours. The device may be a step toward the development of new organs grown from a patient's own cells, the researchers said on Tuesday.

The finding, reported online July 13th in Nature Medicine, is the second in a month from researchers seeking ways to regenerate lungs from ordinary cells.

In the latest study, Dr. Harald Ott and colleagues at Massachusetts General Hospital and Harvard Medical School in Boston removed the cells from rat lungs to leave scaffolds with acellular vasculature, airways and alveoli.

Then they "seeded" the scaffolding with epithelial and endothelial cells to regenerate gas exchange tissue. Next, they simulated the physiologic environment of developing lung in a bioreactor.

By the fifth day, when perfused with blood and ventilated at physiologic pressures the scaffolds "generated gas exchange comparable to that of isolated native lungs," according to the authors.

When implanted in rats, they worked for up to six hours after extubation, although imperfectly.

The researchers said it may be possible to try the experiment with more embryonic stem cells or induced pluripotent stem cells.

Last month, a team at Yale University in Connecticut implanted engineered lung tissue into rats that helped the animals breathe for two hours.

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Saturday, July 17, 2010

Organ shortage a concern in Canada

The Canadian Blood Services (CBS) was given a mandate by the Federal, Provincial and Territorial Deputy Ministers of Health (excluding Quebec) to develop - in consultation with stakeholders, the public, and the medical community - a recommendation for a new national system for Organ and Tissue Donation and Transplantation (OTDT). Canada is one of the only countries in the western world without a national, coordinated system for organ and tissue donation and transplantation (OTDT). I had an opportunity to speak with Kim Young who is quoted in this article as well as the entire board of directors of CBS and suggested to them that the best way to increase organ and tissue donation in Canada would be to start by establishing a national on-line registry.

By Lana Haight Leader-Post, Saskatchewan News Network

A lack of awareness is behind the continued shortage of human organs available for transplantation, says the head of the program in Saskatchewan.

"We've flat-lined for years and years and years in Canada," said Raylene Matlock, manager of the Saskatchewan Transplant Program, based at St. Paul's Hospital in Saskatoon.

In Saskatchewan, corneas and other types of tissue are retrieved more often than organs from people after they've died. In 2009, tissue was retrieved from 30 deceased donors. Typically, organs are retrieved from about 14 deceased donors each year, says Matlock.

At any one time, about 125 people in Saskatchewan are waiting for some kind of transplant.

While about 5,000 people die annually in Saskatchewan, not all have organs that would be suitable for transplanting, says Matlock.

"An ideal donor is somebody who's been healthy for most of their life and died of a catastrophic event to their brain. Now, a catastrophic event can include many things: an overdose, a trauma, a gunshot wound, a massive stroke or cerebral aneurysm," she said.

And even with suitable donors, not all tissue or all organs are retrieved. From the 14 donors in 2009, 13 livers, five hearts and 19 kidneys, including pairs, were among the organs made available for transplantation.

Matlock would like to see Saskatchewan's donation rate double to 28 deceased donors each year, but to accomplish that, people in the province need to start talking to their family and friends.

"If they have not talked to their family about what their wishes are, sometimes it makes it very difficult at this time for a family to decide what to do," said Matlock.

"Some people aren't comfortable with death, finality. And some aren't comfortable that we're keeping their loved one alive on machines. They have to be educated by us about brain death and what that actually means, that there is no blood flow to the brain. We do tests that confirm it. We do scans that confirm it."

Only the next-of-kin can provide legal consent for organs to be retrieved from someone who has died. A signed organ donor card or a sticker on a health card does not provide that consent for organ donation, says Matlock. Still, for those people who want the cards, they are available from the Saskatchewan Transplant Program offices in Regina at 766-6477 or Saskatoon at 655-5054.

Health-care workers also need to become more aware of their responsibility to encourage organ donation, says Kimberly Young, executive director of organs and tissues for Canadian Blood Services.

"No one would ever dream of not diagnosing an appendix, but often it happens that they don't diagnose the opportunity for organ donation. You would be held accountable if you missed diagnosing an appendix even if it was for someone who was 95 years old," said Young.

"We shouldn't leave it up to the person. We should have a system that says (organ donation) is the responsible and required diagnosis."

The Canadian Blood Services is drafting a document for the deputy ministers of health from the federal, provincial and territorial governments that will recommend ways to increase the rate of organs from deceased donors. Establishing a legally binding national electronic registry for people who want their organs retrieved after death could be one of the recommendations, says Young.

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Thursday, July 15, 2010

Canadian mother donates kidney to casual acquaintance

Thornhill, Ontario single mom of three teenagers donates kidney and now advocates for organ donation


Giving a gift for life. Kathy Laszlo (right) donated a kidney to Terri Quint last month. Ms Laszlo is back at work and feeling fine and wants everyone to consider donating to help others. Staff Photo/Steve Somerville

By Ken Zarzour yorkregion.com

Robyn Quint hung up the phone and turned to her husband.
“Kathy says we can have her kidney.”

“You’re joking,” Saul said, turning to her in shock.

“No, she’s serious. She says we can have it if we want it.”

And that’s how it went down — as casually as if Kathy Laszlo were offering her neighbor a cup of sugar.

The Quint family of Thornhill had struggled through a nightmarish few months.

Their developmentally disabled teenaged daughter, Terri, had experienced kidney failure and was attached to a home dialysis machine for eight hours a day, six days a week.

Robyn and Saul ran the machine at night; the parents did not sleep and their other children coped as best they could.

It would be like this for the rest of Terri’s life, doctors said, if they could not find a donor, and finding a match was proving impossible.

Despite their large and willing families, not one relative was eligible.

So, the offer from a casual acquaintance — who was herself a single mom of three teenagers, one of whom also had special needs — seemed like manna from heaven.

“My husband got on the phone and kept thanking her, over and over,” Ms Quint said.

“And then I told him, enough thanking, let’s get to work,” Ms Laszlo added with a laugh.

Now, just two weeks after the life-saving transplant, Ms Laszlo and Terri sit together on Ms Laszlo’s family room couch in Thornhill, looking the picture of health.

Ms Laszlo is back at work and her lifestyle back to normal, despite the missing kidney.
And while she makes the whole process sound like a piece of cake, it wasn’t exactly.

The first hurdle was persuading the hospital to schedule the surgery at the end of June when her disabled son would be taken care of in camp.

The second involved a battery of tests to ensure she was qualified to donate.

“I was extremely worried that, for some small reason, they would rule me out,” she said.
There were even mental health tests, “so now my kids can’t call me crazy anymore,” she said with a laugh.

“They said I’m sane and I’ve got the papers to prove it,” she added.

“Kathy has been unwavering,” Robyn Quint said looking to her friend with fondness.

Before they took their relationship to this whole new level, they were both simply carpooling moms whose disabled children took part in the same community activities.

The transplant was scheduled for Toronto General Hospital June 25.

Ms Laszlo rested in the pre-op room and marvelled to her teens that she felt so calm.

Trips to the dentist caused her more nerves than this.

After two hours, she awoke from the anaesthetic, the kidney removal complete.

“How’s Terri? And who won the game?” were her first words.

Brazil and Portugal were going head-to-head at the World Cup in South Africa.

It was a good game.

Ms Laszlo, who runs a charity called DANI, which helps find employment and runs social programs for young adults and teenagers with special needs, said she feels as if she has used Toronto General to give life twice — first, when she gave birth to her children, and now, she’s given life again.

It’s a little strange, knowing part of her body is working hard in this young girl’s, but Ms Laszlo feels no pain or after-effects.

It takes three days for one kidney to take over 75 per cent of the function of the missing kidney, she said adding 100 per cent function was not necessary.

“There’s a saying God gave us two kidneys to give one away,” she said.

“If it were my child, God forbid, I would move heaven and earth to find a donor to save him.”

Since then, Terri has been in great health and spirits and, while she can’t verbalize it, she seems aware that her friend’s mom has given her a very special gift.

And Ms Laszlo is telling everyone who will listen about her experience with living organ donation.

“It’s not like I’m waiting for a hero’s welcome,” she said. “I just want people to know how important it is to go on a donor list, even if it’s just to sign the donor card on your driver’s licence.”

She points to her next door neighbour’s cousin, waiting desperately for a donation and “getting sicker and sicker by the minute. There comes a time when you’re too sick to do it anymore. There’s a time limit.”

“People think it’s a life-changing experience to donate an organ, but I’m still able to live the same life, eat the same food, do the same exercise.

“It’s not such a big deal, physically speaking, a couple of weeks of your life, to give another person a chance at life.”

Notes: Living Donor Paired Exchange Programs have been established to match up donors with recipients who are of compatible blood types. For more info go to the following links:
Canada: Living Donor Paired Exchange Registry
United States: MatchingDonors.com


“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Wednesday, July 14, 2010

New York passes bill to allow on-line organ donor registry

Congratulations to the State of New York for implementing this Act that will help to dramatically improve organ and tissue donation. Go to New York Donor Network for more info. This brings to 47 the number of U.S. states that now have on-line donor registration and I've been told that the remaining three are in the process of doing so as well.

NEW YORK ORGAN DONOR NETWORK APPLAUDS GOVERNOR PATERSON’S SIGNING OF ELECTRONIC SIGNATURE ACT

Law Will Result in Drastically Increased Donor Registry Enrollments to Save Lives

New York, NY - July 8, 2010: Governor David Paterson today signed into law an electronic signature bill that will dramatically improve the organ donation process in New York. The law will allow New Yorkers to register online to become organ donors. The bill passed the Assembly unanimously on April 27 and the Senate on May 12. The Electronic Signature Act eliminates the need to download enrollment forms and mail them in.

The statement from Elaine Berg, President and CEO of the New York Organ Donor Network follows:

“This is an historic day for every New Yorker that is waiting for a lifesaving organ. For years, the New York Organ Donor Network has led the fight for an electronic signature. This bill is the key to streamlining the organ donation registration process; once implemented, its effect will be immediate, and will result in countless lives being saved.

“On behalf of the entire New York Organ Donor Network family, I applaud Governor Paterson for signing this bill into law, and giving New Yorkers the tools they need to step up and sign the donor registry in record numbers.

“We thank Senator Duane, Assemblymen Gottfried and Brodsky, and all of the bill’s cosponsors for their continuing leadership in making this dream a reality. We extend our gratitude to the entire Assembly and Senate for unanimously passing this landmark legislation.”

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Tuesday, July 13, 2010

Infectious disease specialists complement each other

Dr. Atul Humar, left, and his wife, Dr. Deepali Kumar, both physicians and infectious disease researchers, work in a lab at Katz Group Centre for Pharmacology on the University of Alberta campus. Photograph by: Shaughn Butts, The Journal, Edmonton Journal


Super' duo together, at home and at work


By Chris Zdeb, Edmonton Journal

Physician-scientists Atul Humar and Deepali Kumar are the only husband-wife transplant infectious disease team in the world.

Transplant patients are subject to infections because of the powerful drugs they take to suppress their immune systems so they won't reject the new organs. Humar researches how herpes viruses cause disease in these immunocompromised people. Kumar looks at how transplant patients respond to vaccines.

The similarity of their work allows them to manage each other's patients or research projects when necessary.

"They're a super couple who work almost seamlessly with each other, even though they very keenly maintain their own identity," says Dr. Barbara Ballermann, chairwoman of the University of Alberta department of medicine, where they work. "That type of relationship is really uncommon."

Their team approach continues at home, where they are parents to son Dino, 6, and daughters Sapna, 9, and Sonika, 4.

"We spend a lot of time together," says Humar, prompting laughter from his wife.

Adds Kumar: "Ideas don't occur to somebody only from 9 to 5, so if an idea occurs in the evening, then it's very easy to bounce ideas off each other" -- when they're not running off to take the kids to soccer, swimming, taekwondo or piano, that is.

Their offices are next door to one another in the Katz Group Centre for Pharmacology. They also work side by side in a lab on another floor.

Told that some might see this as too much togetherness, the pair smiles and nods.

"Couples who get along really well with each other say, 'Oh that's really cool,' and those that don't get along go, 'How do you tolerate that?' " Humar says, laughing.

"Like, 'How do you stand to be with each other for 24 hours?' So we get both reactions," Kumar adds.

Humar and Kumar have a "very compatible temperament" that's important to their success, not only as husband and wife, but as scientists, observes Dr. Lorne Tyrrell, a former dean of the faculty of medicine and dentistry who also works with infectious diseases at the U of A. He has known them for 18 months.

Humar says he's good at coming up with ideas, but not at implementation and logistics, which are Kumar's strong points.

"I think that's why our research has worked so well together because we kind of complement each other's strengths and weaknesses," he says.

The couple have an easy rapport, and often finish each other's sentences, as happens sometimes when you've been married for 10 years.

They share interests in Indian music and Bollywood movies. Kumar is such a fan, she doesn't think twice before answering she'd like to be a leading Bollywood actress if she wasn't a physician-scientist.

"If somebody came and said, 'You have a part in a movie,' I'd go, 'I'm there,' " she says, laughing. "But then I'd come back and do my day job."

Humar, a space buff who is into Star Trek and Star Wars, says he would be an astronaut.

Their lives became entwined when they met through their parents, who are friends and academics at Carleton University in Ottawa. Kumar was 18 and Humar 22.

They have so many "really freaky" things in common -- among them, the similarity of their last names, and their dads sharing the same birthday -- that Kumar says it's almost as if they were fated to meet and be together.

But they lost touch as education and work took them to different places in Canada and the U.S., until their infectious disease specialties brought them together again.

"We were friends for a long time," Humar, 41, says.

"We lived in different cities; we didn't really date. One day, I guess it was sort of time to get married," finishes Kumar, 37.

Humar was at the University of Toronto, where he pioneered the first transplant infectious diseases program in Canada, when Kumar started working there in 2004.

They moved to Edmonton in 2007 after the U of A came calling with positions and lab space.

Humar is the director of the transplant infectious diseases program and an associate professor of medicine.

Kumar is an assistant professor in the division of infectious diseases. (Her work was recently recognized with an award from the American Society of Transplantation.)

Their stars will continue to rise, says Ballermann, noting that because of how long it takes to train in medicine, people in their early 40s are still considered fairly young.

"They may not have achieved the status of Wayne Gretzky in medicine, but they're on the same team," she says.

Besides finding their ideal jobs here, the couple, who have a five-minute commute from home, also found the work-life balance they were looking for.

"It's just a more kid-friendly place (than Toronto) basically," Humar says. "It allows us to do what we want to do at work and, at the same time, allows us to spend time with the kids and ensure that they're able to do all the things they want to do, and yet, spend time as a family.

"Work is important and we put 110 per cent into work, but our life revolves around our kids. Family is always No. 1."

Many people, especially academics, are very driven and their work is kind of an overriding thing, he continues. "But I think the main message here is that you can actually do both (be a parent and an academic), and do them well. It's all about what you decide are your priorities."

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Monday, July 12, 2010

Specialist flown to Quebec from Toronto for artificial lung surgery

Sherbrooke man survives rare lung surgery

Procedure is the first of its kind in Quebec history

CBC News

Doctors in Sherbrooke, Que. are hopeful that a man suffering from severe pneumonia may have a fighting chance after surviving a rare lung procedure.

The man is believed to be the first in Quebec to have survived the surgery to attach an external artificial lung, known as a Novalung, to his leg.

The device is meant to perform some of the functions of a normal lung, including clearing the body of carbon dioxide and pumping a small amount of oxygen into the body through the arteries and veins in the leg.

The patients involved in the first two surgeries in Quebec did not survive the procedure.

Doctors said the device can only operate for up to 29 days.

“It's going to be there for a short period of time, after a while we're going to take it out. The device is just to let the lung recover from the pneumonia,” said Dr. Marco Sirois, a thoracic surgeon with Sherbrooke University Health Centre.

The 47-year old patient, who cannot be identified due to privacy regulations, is still in critical condition.

His daughters said they remain optimistic, despite the fact that their father is still seriously ill.

"We’re trying to stay realistic," said Noémie, one of the patient's daughters.

"But the surgery has given us hope,” said the other daughter, Jessica.

The surgery is so rare in Quebec that doctors in Sherbrooke sought the help of a specialist from Toronto, who was flown in from Montreal in a Quebec provincial police helicopter.

The Novalung is also sometimes used to help patients who are waiting for a lung transplant.

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Saturday, July 10, 2010

Man donates part of liver to dad while awaiting second child

Peter Boughan donated 70 percent of his liver to his father Robin

By CARMELA FRAGOMENI, THE HAMILTON SPECTATOR, Ontario, Canada

Fatherhood has extraordinary meaning in Burlington's Boughan family.

Son Peter, 30, recently donated 70 per cent of his liver to his father Robin, 63. It saved Robin's life.

In a week or two, Peter will become a father again when his wife Jen gives birth to their second child.

"My dad's health was going down quite rapidly and I love my dad," said Peter about undergoing the transplant despite having 15-month-old daughter Leah to care for and another baby on the way.

"I don't think I could live with myself happily if I didn't do anything and I could have made a difference."

Peter, a supply teacher, was the third person tested for suitability. The first, Robin's brother who 21 years ago donated bone marrow to help Robin to fight leukemia, turned out to be a no-go. Same for Robin's daughter.

In all, seven family members, friends and fellow churchgoers at Hamilton's Philpott Memorial had offered part of their liver. Many more in Hamilton, Burlington, the U.S. and Africa offered their prayers after hearing about Robin through friends, family or the church network.

"This is the answer to the prayers of many people," Robin said. "It became a wonder to me to hear from someone that so and so was praying for me.

"The whole thing has an emotion for me that is very gripping. I get very emotional these people would do this for me ... and to think my son would do what he did for me ..."

Robin, a retired teacher and former art department head at Sherwood Secondary in Hamilton, was diagnosed in March 2009 with cirrhosis.

"He doesn't even drink," said his wife Sandy.

Doctors who did the transplant at Toronto General blamed non-alcoholic fatty liver disease. His Hamilton doctors thought it was something else. Whatever the cause, the result was the same: he needed a new liver or he would die.

Robin was put on a list for a transplant this November when his symptoms worsened. He moved up when his kidneys started to fail and water retention bloated him severely. By March 31, doctors bumped another patient out of surgery to make room for Robin's operation because he was too sick to wait anymore.

"It was very stressful," Sandy said. "Because you have both of them in surgery at the same time, on the same day, and they are long surgeries."

Peter's surgery was seven hours, Robin's 13.

"Even though they tell you Peter's healthy, it's still stressful," Sandy said. "He has a wife who's pregnant and a daughter ..."

Both she and Robin urge people to sign their donor card and make their wishes for organ donation clear to their families, especially when it comes to livers.

Once in, liver transplants have the lowest chance of rejection among transplants and 90 per cent of the removed portion used in the transplant grows back within 12 weeks, doctors told them.

"They are looking for liver donors all the time," Sandy said.

From a statistical point of view, the transplant is relatively risk-free, said Robin. Even 80-year-olds can donate because the liver is an organ that regenerates itself.


“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Friday, July 09, 2010

H1N1 Can Cause Substantial Illness, Death in Transplant Recipients

Doctor's Guide
NEW YORK -- July 8, 2010 -- Influenza A(H1N1) caused substantial disease and death in solid organ transplant (SOT) recipients during 2009-2010. However, early treatment (within 48 hours) with antiviral therapy resulted in lower rates of hospitalization and reduced the number of admissions to intensive care by almost two-thirds.

Wherever possible, early antiviral treatment for symptomatic patients during future outbreaks along with preventive measures such as vaccination might offer protection for this high risk population, according to a study published online first and appearing in an upcoming print issue of The Lancet Infectious Diseases.

Transplant recipients infected with H1N1 are probably more likely to develop severe disease than the general population. Although many guidelines document the importance of influenza infection in organ transplantation, studies on the impact of influenza and the use of antiviral treatment in SOT patients are lacking. In addition, conflicting outcomes have been reported about the severity of disease resulting from influenza infection.

To provide more evidence on clinical outcomes in people who have had a SOT, Deepali Kumar, MD, University of Alberta, Edmonton, Alberta, and colleagues assessed 237 transplant recipients infected with H1N1 to identify factors leading to admission to hospital and intensive care unit (ICU), and other complications.

The researchers surveyed 154 adults and 83 children from 26 transplant centers in the US, Canada, and Europe who had received organ transplants (kidney, heart, lung, liver, and others) and had H1N1 between April and December 2009. Information on type of transplant, symptoms, diagnosis, and treatment were collected, and factors leading to pneumonia, admission to hospital, and ICU were calculated using statistical models.

Patients received their transplant a median 3.6 years before being infected with H1N1. Overall, 167 (71%) of 237 patients were admitted to hospital, 37 (16%) were sent to the ICU (of whom 21 needed mechanical ventilation), and 10(4%) died.

Importantly, findings showed that early antiviral treatment, primarily with oseltamivir, was linked with a reduced likelihood of ICU admission (7 of 90 patients treated within 48 hours vs 28 of 125 patients treated after 48 hours), admission to hospital, need for mechanical ventilation, and death.

The results confirmed previous research showing a high risk of pneumonia, with almost a third of patients in this study contracting pneumonia. Interestingly, children were less likely to present with pneumonia compared with adults (13 of 81 children vs 60 of 149 adults).

"Pandemic influenza A H1N1 resulted in a spectrum of illness ranging from mild and self-limiting to severe disease in recipients of solid-organ transplants…starting treatment with antiviral drugs early is important for reduction of morbidity and mortality in this highly susceptible population," the authors wrote. "For example, during periods of transmission, transplant patients presenting with signs and symptoms that are compatible with influenza should probably start empirical treatment with antiviral drugs before the diagnosis is confirmed."

"Almost a third of the patients in our cohort reported contact with an ill household member before their own illness," they continued. "In this setting, postexposure chemoprophylaxis might be an option…Vaccination of both transplant patients and their household contacts is probably an important preventive measure since vaccine responses might be suboptimum after transplantation."

SOURCE: The Lancet Infectious Diseases

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Thursday, July 08, 2010

Organ transplants can extend a patient's life by years; donors are always needed

This is an excellent overview of organ and tissue donation and transplantation that answers questions about how organs are matched and allocated as well as how to become a donor.

Cleveland Plain Dealer guest columnist Dr. Robert Schilz

Organ transplantation is the act of taking an organ from a living or deceased donor and using it to replace a dysfunctional or damaged organ in a recipient's body. The surgical techniques required for this procedure have been around for a long time, however the problem has always been rejection of the new organ by the body receiving it.

The first successful organ transplant was in 1954, and it involved a kidney between living twin brothers. After drugs that help the body not reject the new organ (immunosuppressants) were developed, a large number of transplantations occurred, all having much more success than their earlier counterparts. Now transplantations can extend a patient's life by several years with proper immunosuppressive (drug) therapy.

    Some other interesting facts about organ transplantation:
  • Hearts, intestines, kidneys, livers, lungs, and pancreata can all be transplanted. Other promising initial transplants have included trachea and face transplantation.
  • About 81 people receive an organ transplant every day in the U.S.
  • In 2008, more than 28,000 patients began new lives thanks to an organ transplant.
  • Living donors can donate a kidney or parts of their liver or lung.
  • Matching donated organs to patients

    When a potential organ donor is identified a transplant coordinator from an organ procurement organization enters medical information about the donor into the United Network for Organ Sharing (UNOS) computer system. The system then matches the donor’s medical characteristics with the medical information of candidates awaiting a transplant. The computer generated a ranked list of patients for each organ recovered from the donor. These “matches” are based on many things which may include:

  • Level of illness
  • Medical urgency of the transplant candidate
  • Time spent on the waiting list for some organs
  • Biological similarities between the donor and the candidates (such as organ size, blood type, and genetic makeup)
  • Candidate’s availability to be transplanted immediately
  • Waiting for an organ – How long does it take? Patients added to the national organ transplant waiting list may receive an organ that day, or they may wait years. Factors affecting waiting time include:

  • How well the donor and recipient “match”
  • How ill the patient is
  • Availability of donors compared to the number of patients waiting
  • To gauge waiting time, UNOS publishes waiting time statistics by geographic region, sex, age, blood type and ethnicity.


Can a patient from another country receive a transplant in the U.S.?

Yes. Patients can travel from other countries to the U.S. to receive transplants. Once accepted by a transplant center, international patients receive organs based on the same policies as those that apply to U.S. citizens. These types of transplants are limited in number.

How to become an organ, eye and tissue donor

There is an urgent need for registered organ, eye and tissue donors in Ohio and across the United States. One organ donor can save eight lives, while one tissue donor can enhance the lives of more than 50 people. Unfortunately, 107,000+ men, women and children nationwide are currently waiting for life-saving organ transplants. Thousands on that waiting list live in Ohio.

To become a registered organ, eye and tissue donor, do one of the following:

  • Say yes to donation at the BMV when renewing your driver license
  • Register online at LifeBanc.org or call for a registration form at 216-752-5433
  • Include donation in your living will
  • Inform your family about your decision
For more information about organ donation, please contact:
LifeBanc.org
Donate Life Ohio
Donate Life America

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Wednesday, July 07, 2010

Scottish girl gets new lungs after ten false alarms

Victoria Glen looks a picture of health, just weeks after have life-saving transplant surgery

“The woman who gave me the lungs is my guardian angel sitting on my shoulder. I only know her name and how she died.

By Caroline Wilson, Evening Times

The 28-year-old was given a double lung transplant in May after ten false alarms and seven unsuccessful attempts to operate.

And she says she can’t wait to dance properly for the first time in years at her celebratory “New Lungs” party.

The Strathclyde University graduate is urging the public to join the organ donor register as charities warn the gap between organ supply and demand is continuing to grow.

Three people die every day in the UK waiting for a transplant.

She said: “The most precious gift that can be given is to give someone their life back before it’s too late.

“It means the world to me and so many people out there.”

Victoria, who lives in Merchant City, Glasgow, was diagnosed with Cystic Fibrosis at the age of six months.

By the time she reached 26, the condition had ravaged her lungs and she was told a double lung transplant was her only hope.

Her lungs were functioning at 20%, she was dependent on oxygen twenty four hours a day and was frequently in hospital fighting life threatening chest infections.

After almost two years on the waiting list, she underwent major surgery to transplant two healthy lungs at Newcastle’s Freeman hospital.

Previous attempts to operate had been unsuccesful because the the organs had either been damaged, or she wasn’t well enough for the operation.

Victoria, said: “I remember when I woke up I didn’t feel any different and I thought, have they done it?

“I started to feel better after about a week and now I feel really really good. I’m not coughing anymore.

“I thought it was never going to happen.

“The woman who gave me the lungs is my guardian angel sitting on my shoulder. I only know her name and how she died.

“The best thing about the operation, is just being able to just walk around. Before the operation I was spending most of my time in hospital.

“What I’m most looking forward to is dancing at my New Lungs party. I used to do a lot of tap and ballet when I was a lot younger but haven’t been able to for a long time. “

Victoria is also planning to return to work as a part-time drama teacher in a matter of weeks and hopes to eventually teach full-time.

Gerard Falsey is hoping it will be fourth time lucky for him, after three unsuccesful attempts this year by surgeons to give him a lung transplant.

Gerard, also 28, from Hamilton, South Lanarkshire, has a rare and progressive lung condition that has left him completely reliant on his family.

He was born five weeks prematurely with one under-developed lung.

Shortly afterwards both his lungs collapsed and he wasn’t expected to survive.

However he rallied round and recovered but spent most of his childhood in and out of hospital after surviving several bouts of pneumonia.

His condition deteriorated four years ago at the age of 24 and he was forced to give up his job as a debt counsellor, and his cherished Celtic FC season ticket. He now relies on a powerful cocktain of steroids and antibiotics to stay alive.

He said: “I’ve been down to Newcastle three times but the lungs weren’t healthy enough. It’s very hard emotionally and physically because you are psyched up for it.

“I’ve got to keep hopeful about it though.

“It would mean everything to me to get a transplant. It’s a chance to have a normal life.

“To go on the register is an unbelievable thing that you can do for more than one person.

“It’s a real chance to be a hero.”

Although the majority of the population support the concept of organ donation, only 28 per cent of the population are on the register.

Emily Thackray, of transplant charity Live Life Then Give Life said: “It’s something a lot of us don’t really think about, even though any one of us could need a transplant at some point.”

To register as an organ donor go to NHS Organ Donor Register or call 0300 123 23 23. To find out more about organ donation you can visit http://www.lltgl.org.uk.

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Tuesday, July 06, 2010

Families urged to join Organ Donor Register

With 3 people dying every day in the UK and 18 dying in the US while waiting for an organ or tissue transplant this article is a good reminder of the importance of registering to be a donor and encouraging your friends and family to do likewise. Register to be a donor at the bottom of this post.


By Helen Rae, Evening Chronicle, ChronicleLive.co.uk

FAMILIES in the region are being encouraged to take the time to have a ‘Heart to Heart’ discussion about organ donation.

With three people dying every day while waiting for an organ, NHS Blood and Transplant (NHSBT) is calling for people to think seriously about joining the Organ Donor Register.

In the North East 26% of the population have signed up, meaning 809,184 people have become part of the NHS-based register.

Themed as Heart to Heart, National Transplant Week, which runs until this Sunday, gives people the chance to sit down with their friends and relatives to talk about the issue.

The importance of organ donation is highlighted by the remarkable story of Claire Crozier and her brother Peter Dobing.

Claire, 34, was diagnosed with cardiomyopathy four years ago and doctors at Newcastle’s Freeman Hospital said she urgently needed a new heart.

The mother-of-two had a transplant in 2006, but she suffered a major blow when her older brother, Peter, was diagnosed with the same condition.

Peter, who works in customer services, underwent a heart transplant last year at the same hospital, carried out by the same surgeon who treated his sister.

Claire, of Gosforth, said: “I would like to say a big thank you to everyone who has already signed up to the Organ Donor Register – it is a remarkable thing to do.

“It means so much to me and my family that both Peter and I had the opportunity to continue our lives because we were given heart transplants.

“I encourage as many people as possible to sign up – it really does save lives.”

A Heart to Heart downloadable meal pack is available to get people talking together about organ donation over a tasty meal.

It includes recipes devised by TV chef Lawrence Keogh who had a kidney transplant in 2000.

He said: “Having had a kidney transplant myself, I know the difference it can make.

“I urge everyone to get involved in Transplant Week by having a Heart to Heart conversation with their loved ones and thinking about whether you would be willing to sign the Organ Donor Register.”

Anthony Clarkson, assistant director of organ donation and transplantation, said: “We’ve seen a big rise in the number of people in the UK signing up but it’s still not enough – three people are still dying every day.

“So make sure you download the meal pack, tell your family and friends to do the same, and please take two minutes to support Heart to Heart week by signing up today.”

For more information or to download the Heart to Heart meal pack, visit http://www.organdonation.nhs.uk/transplantweek


“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Sunday, July 04, 2010

Happy 4th of July


Happy Independence Day to my American friends as you celebrate the 234th birthday of your wonderful country. I hope you have a great weekend with the celebrations, fireworks, parades and bbq's.

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Saturday, July 03, 2010

Australian man gets transplant of small intestine, liver, pancreas and duodenum

Surgeons in Melbourne have completed Australia's first full intestinal transplant.

ABC News

The 12-hour multi-organ transplant was completed at Melbourne's Austin Hospital early on Saturday morning.

Brendan Cole, 32, had been suffered worsening intestinal failure since childhood and has endured more than 30 operations.

Surgeons replaced his small intestine, liver, pancreas and duodenum in an operation regarded as the most complex and risky of all transplant procedures.

Mr Cole is in a serious but stable condition in intensive care but doctors say it will be months before they know whether the transplant has been a success.

Head surgeon Professor Bob Jones says there is now a high risk of organ rejection and infection.

"The bowel has been really difficult to transplant. It's the last frontier of transplantation because the bowel is extremely sensitive," he said.

"You can have a fantastic operation and a fantastic recovery and then a month down the track get a nasty infection that could be potentially life-threatening.

"So Brendan won't really be out of the woods [yet]. We'll really relax in about three months."

Professor Jones says Mr Cole may have had only months to live before the high-risk surgery.

"Brendan probably had less than a year to live, probably six months, so ... it's lifesaving for him," he said.

"He spent the last 12 years of his life hooked to IV line and ... unable to eat.

"Once he's recovered, we can let him out of the hospital, he can go down to the grocery shop, buy some food, cook it and eat it.

"It'll have an extraordinary affect on his life."

Mr Cole says he is looking forward to getting married and living a normal life.

"This morning I tried to get the nursing staff to pinch me a few times cos I thought maybe something had gone wrong, but then everyone said 'oh no it went really really well'," he said.

"It's ridiculous to say it's probably been one of the best days of my life and it's only going to get better from here."

Mr Cole has thanked the doctors who saved his life.

"It's hard to explain how professional and how comfortable the team at the Austin have made me feel," he said.

"They're so dedicated. Much thanks goes to them - they are an amazing team."

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Kansas donor law changed July 1

I've been stressing the importance of talking to your family and telling your loved ones about your desire to be an organ and tissue donor. The reason is that almost all jurisdictions allow families to make the final decision as to whether or not to donate their loved one's organs and tissues for transplantation, regardless of whether or not one has registered to be a donor. Now, this new Kansas law changes the rules and makes the donor's intent legally binding on the organ procurement organization to harvest that person's organs upon their death. This should have an immediate effect on the donation rate because presently some families refuse to allow organ donation, especially if they are distraught and can see their loved one's chest breathing even though they are on life support to maintain viability for organ removal.

By Catherine Faimon | Publisher The Osage County Herald-Chronicle Online

A new law will take effect July 1, for which all Kansans of driving age should understand. Kansas Governor Mark Parkinson signed into law House Bill 2486, that changes the statewide organ and tissue donor registry from a first-person intent, to first-person consent.

Before this law was passed, it was left to the license holder to talk to family members about the desire or intent to become an organ donor, in the event of an untimely death. With the new law, a person who says “yes” to having their name placed on the Kansas organ and tissue donor registry, at the time of obtaining or renewing a driver’s license, will be legally bound to allow an organ procurement organization to harvest that person’s organs upon their death. Family members of that person will not be involved in decisions regarding organ donation, unless the person is under age 18, as the registry will be a binding document in the court of law.

House Bill No. 2486 was amended and signed into law in May, after proponent of the bill, Midwest Transplant Network (MTN) CEO Rob Linderer, introduced it to the Senate Committee on Public Health and Welfare.

Linderer, along with attorneys for MTN and the National Kidney Foundation, said the amendment “would strengthen and clarify the provisions of the Kansas Uniform Anatomical Gift Act regarding decisions to donate anatomical gifts prior to death and that the first-person registry would provide a more effective mechanism for donors to have their desires concerning the donation of organs registered and recognized.”

In an interview with The Herald-Chronicle last week, Linderer said, “A first-person consent registry upholds an individual’s decision to donate as legally-binding and assures that no one can overturn or disregard the individual’s decision.

“The passage of new legislation in Kansas, transferring the statewide registry to first-person consent is a milestone in fulfilling Midwest Transplant Network’s mission,” he said. “What better way to celebrate the power to gift life and honor donors and their families than new laws fully respecting an individual’s donor designation.”

Midwest Transplant Network Media and Relations Specialist Erin Gregory told The Herald-Chronicle, “With first person registry, nobody can disregard a person’s wishes. It is legally binding for Midwest Transplant, it’s legally binding for the hospitals, and legally binding for the loved ones. An individual can certainly change their mind, you can take your name off the registry or join the registry, all through our website. This is a way to let your loved ones know what your decision is.”

How to register

Beginning July 1, Kansans who obtain a new driver’s license or renew their license, will be asked at that time if they want to place their name on the donor registry. The symbol of a heart and the words “Organ Donor” will be added to the license, and their name will be added to the new registry.

Linderer indicated there are approximately 500,000 Kansans whose names appear on the current registry, although some of those names may be duplicates or people who have died or moved out of state.

He said, “We are hoping that the new Kansas registry will be up and operational by Sept. 1. All Kansans who have previously signed up in the intent registry will need to re-register on the consent registry. No names will be transferred from the old registry to the new registry without active participation of an individual.”

Linderer said instead of his organization being the sole proprietor of the registry, they have opted to contract with an outside firm in Jefferson City, Mo., to maintain the database. “We want to hold ourselves accountable and be trustworthy in the public’s eye,” he said.

Another way to add your name to the registry is to visit www.mwtn.org, download and fill out the enrollment form and mail or fax to Midwest Transplant Network.

A separate website, www.DonateLifeKansas.org, will also be set up by Sept. 1, and will have an e-mail address for correspondence related to signing up or removing a name from the registry.

Removing your name

Once a person’s name is entered into the new registry, they become legally bound to donate their organs and tissue, in the event of being declared brain dead, or if death is imminent. A donor may revoke the gift by directly accessing the registry website, where they will be asked to put into writing, their desire to be removed. To maintain authenticity of a person’s desires, MTN will have a procedure in place to validate the person’s request.

The symbol will remain on the driver’s license until the next renewal date, and should not be marked through. A new license, one without the symbol, may be obtained at local Department of Motor Vehicles offices, for a fee.

Misperceptions about organ donation

One of the most common misperceptions about organ and tissue donation held by the public is that a patient’s level of care in a hospital would be diminished, if the doctors knew the patient wanted to donate organs and tissues.

“The staff at the hospital who are responsible for taking care of a patient coming into the hospital … are totally different than the staff from my organization, or a transplant team, who would be involved with removing the organs,” Linderer said. Strict federal and state regulations are in place, for hospital staff, as well as for organ procurement staff, to prevent conflicts of interest among the groups.

“A physician who is in attendance at the time of a patient’s death cannot participate in the procedures for removing an organ or transplanting an organ or a part into another patient at that hospital. The reality is, there’s only about one percent of patients who die that can be organ donors,” he said. “It’s quite an amazing statistic when you look at the number of overall deaths.

“There is a tremendous shortage of organs and people die every day on the waiting list. Out of the 22,000 death referrals that take place in our service area, only approximately 200 are able to be organ donors, and another 700 are able to donate some type of tissue.”

Another misperception is that a person who has donated organs and tissues is unable to have an open casket funeral.

“The experience we’ve had is that the typical attire a person is clothed with at an open casket funeral situation, does not interfere with organ or tissue donation,” Linderer said.

“We talk with families at the time the donation is proceeding, to find out what their plans are for funeral arrangements, even to the extent of their loved one’s attire for the funeral. For example, if they wanted to bury their loved one in a short sleeve shirt, we would not take bones or tissues from the lower arms that would interfere with the ability to wear that attire.”

About Midwest Transplant Network

Midwest Transplant Network is an organ procurement organization, founded in 1973. The not-for-profit corporation employs approximately 100 full-time staff and another 25 part-time employees. Its territory serves Kansas and the western two-thirds of Missouri. The company’s mission is to save lives through organ and tissue donation and transplantation. Midwest Transplant Network strives to educate and inform the community about the need for transplantation.

Midwest Transplant Network is in the process of updating its website and educational materials to reflect information specific to this new law in Kansas.

Linderer said MTN staff will meet with Kansas Department of Motor Vehicle management staff and county treasurer staff in the near future, to “bring them up to speed” and provide brochures and information about this change in Kansas law.

For more information, call (888) 744-4531, or visit http://www.mwtn.org

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Friday, July 02, 2010

Cyclosporine Side Effects Linked to Risk of Cancer After Liver Transplant

AboutLawsuits.com

A study by Dutch researchers seems to indicate that the organ transplant drug Cyclosporine may increase the risk of cancer among liver transplant recipients.

The findings were published in this month’s issue of the medical journal Liver Transplantation, looking at the rate of new cancer malignancies that occur after patients receive new livers. Researchers say the data they collected indicates that cyclosporine cancer risk is dose-specific, meaning that the more of the medication a patient receives, the higher the risk of cancer.

Cyclosporine is an immunosuppressant that helps prevent the body from rejecting transplanted organs by weakening the immune system. It was approved for use by the FDA in 1983 and was originally developed by Sandoz, now known as Novartis, under the brand name Sandimmune.

In the latest study, researchers performed a retrospective analysis on 385 liver transplant patients between 1986 and 2007. They discovered that 50 of those patients, or 13%, developed a de novo (new) cancer after the transplants. When they looked at the therapies the patients had received, researchers determined that the key risk factor appeared to by the use of cyclosporine.

Researchers also found that the cancer risk was highest in patients who received transplants in recent years, and among those under 50 years of age. They determined that the increase was associated with a change in cyclosporine treatment that increased the amount of the drug they were receiving.

The cancers that followed in the wake of cyclosporine treatments were also more aggressive when compared to patients taking other transplant treatments who developed cancer, researchers said.

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You

Thursday, July 01, 2010

Happy Canada Day


Happy Canada Day to all Canadians as you celebrate the birth of the nation in 1867. I hope you enjoy the parades, BBQs and fireworks. Merv.

“You Have the Power to Save Lives – Register to be an organ and tissue donor & Tell Your Loved Ones of Your Decision”
Register to be a donor in Ontario or Download Donor Cards from Trillium Gift of Life Network. NEW for Ontario: recycleMe.org - Learn The Ins & Outs Of Organ And Tissue Donation. Register Today! For other Canadian provinces click here
In the United States, be sure to find out how to register in your state at ShareYourLife.org or Download Donor Cards from OrganDonor.Gov
In Great Britain, register at NHS Organ Donor Register
In Australia, register at Australian Organ Donor Register
Your generosity can save up to eight lives with heart, kidneys, liver, lungs, pancreas and small intestine transplants (see allotransplantation). One tissue donor can help 75 to 100 other people by donating skin, corneas, bone, tendon, ligaments and heart valves

Has your life been saved by an organ transplant? "Pay it forward" and help spread the word about the need for organ donation - In the U.S. another person is added to the national transplant waiting list every 11 minutes and 18 people die each day waiting for an organ or tissue transplant. Organs can save lives, corneas renew vision, and tissue may help to restore someone's ability to walk, run or move freely without pain. Life Begins with You